Deltamethrin induces hippocampal neuronal MEK/ERK signaling pathway and apoptosis leading to neurobehavioral disorders in mice

Deltamethrin induces hippocampal neuronal MEK/ERK signaling pathway and apoptosis leading to neurobehavioral disorders in mice

Objective To investigate the potential role and molecular mechanisms of the MEK/ERK signaling pathway and apoptosis in the neurotoxicity induced by short-term exposure to deltamethrin (DM). Methods Forty adult male C57BL/6J mice were randomly divided into control group, low-dose DM group (4.5 mg/kg)...

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Bibliographic Details
Main Authors: WU Minjia, CHEN Yang, MA Peixuan, WEI Lexing, PAN Wen, DENG Yaqin, CHEN Weiqi, HUANG Xiaowei
Format: Article
Language:zho
Published: Editorial Office of Journal of Guangxi Medical University 2025-02-01
Series:Guangxi Yike Daxue xuebao
Subjects:
deltamethrin
neurotoxicity
learning and memory abilities
apoptosis
mek/erk
Online Access:https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2025.01.006
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https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2025.01.006

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