VISTA is a potential target for immunotherapy in B-cell acute lymphoblastic leukemia in children

Abstract Immune checkpoints expressed by immune cells are critical mediators of immune suppression in cancer. Recently, the role of VISTA, an immune checkpoint, in suppressing T cells has been highlighted in several studies. However, its involvement in B-cell acute lymphoblastic leukemia (B-ALL) rem...

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Bibliographic Details
Main Authors: Nourhan K Mohamed, Mohamed A El-Mokhtar, Asmaa M Zahran, Gamal Fadl Mahmoud Gad, Reham Ali Ibrahem
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-08164-2
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