Localized In Vivo Electro Gene Therapy (<i>LiveGT</i>)-Mediated Skeletal Muscle Protein Factory Reprogramming

Localized In Vivo Electro Gene Therapy (<i>LiveGT</i>)-Mediated Skeletal Muscle Protein Factory Reprogramming

Gene electrotransfer (GET) has gained significant momentum as a non-viral gene delivery method for various clinical applications, primarily in the cancer immunotherapy and vaccine development space. Preclinical studies have demonstrated exogenous gene delivery and expression in various tissues, incl...

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Bibliographic Details
Main Authors: Jacob Hensley, Michael Francis, Alex Otten, Nadezhda Korostyleva, Tina Gagliardo, Anna Bulysheva
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Applied Sciences
Subjects:
insulin
gene electrotransfer
<i>liveGT</i>
gene therapy
glucose
protein replacement therapy
Online Access:https://www.mdpi.com/2076-3417/14/23/11298
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