Unraveling the Mechanism of Impaired Osteogenic Differentiation in Osteoporosis: Insights from <i>ADRB2</i> Gene Polymorphism

Unraveling the Mechanism of Impaired Osteogenic Differentiation in Osteoporosis: Insights from <i>ADRB2</i> Gene Polymorphism

Osteoporosis is characterized by increased resorption and decreased bone formation; it is predominantly influenced by genetic factors. G-protein coupled receptors (GPCRs) play a vital role in bone homeostasis, and mutations in these genes are associated with osteoporosis. This study aimed to investi...

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Main Authors: Olga Krasnova, Julia Sopova, Anastasiia Kovaleva, Polina Semenova, Anna Zhuk, Daria Smirnova, Daria Perepletchikova, Olga Bystrova, Marina Martynova, Vitaly Karelkin, Olga Lesnyak, Irina Neganova
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
osteoporosis
G-protein coupled receptors
mesenchymal stem cells
osteogenic differentiation
beta-2-adrenergic receptor
Online Access:https://www.mdpi.com/2073-4409/13/24/2110
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https://www.mdpi.com/2073-4409/13/24/2110

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