Regorafenib and glioblastoma: a literature review of preclinical studies, molecular mechanisms and clinical effectiveness

Glioblastoma IDH wild type (GBM) is a very aggressive brain tumour, characterised by an infiltrative growth pattern and by a prominent neoangiogenesis. Its prognosis is unfortunately dismal, and the median overall survival of GBM patients is short (15 months). Clinical management is based on bulk tu...

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Bibliographic Details
Main Authors: Maria Patrizia Mongiardi, Roberto Pallini, Quintino Giorgio D'Alessandris, Andrea Levi, Maria Laura Falchetti
Format: Article
Language:English
Published: Cambridge University Press 2024-01-01
Series:Expert Reviews in Molecular Medicine
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Online Access:https://www.cambridge.org/core/product/identifier/S1462399424000085/type/journal_article
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