Defects in hair cells disrupt the development of auditory peripheral circuitry

Abstract Deafness is the most common form of sensory impairment in humans and frequently caused by defects in hair cells of the inner ear. Here we demonstrate that in male mice which model recessive non-syndromic deafness (DFNB6), inactivation of Tmie in hair cells disrupts gene expression in the ne...

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Bibliographic Details
Main Authors: Riley T. Bottom, Yijun Xu, Caroline Siebald, Jinsei Jung, Ulrich Müller
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55275-x
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