鼻咽癌细胞的糖皮质激素受体含量及受新酮醛的影响
以~H-地塞米松(~3H-dexamethasone,~3H-Dex)为放射配基,测定鼻咽癌细胞糖皮质激素受体(GCR)含量,结果当用地塞米松(Dex)非标记配基作竞争性试验时,GCR水平较高,而且低分化鼻咽癌上皮细胞(CNE-Ⅱ)GCR含量明显高于高分化细胞(CNE-I)(P<0.05);用新酮醛、新鱼腥草素或多糖替换Dex作竞争物时,CNE-Ⅰ细胞由于受新酮醛作用影响,GCR含量明显高于Dex作用时的含量(P<0.05);CNE-Ⅱ细胞GCR含量提示新酮醛、新鱼腥草素、Dex三者的作用大致相同(P>0.05)。此外,以CNE-Ⅰ和CNE-Ⅱ作竞争物时均测不到GCR含量,且...
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| Format: | Article |
|---|---|
| Language: | zho |
| Published: |
Editorial Office of Journal of Sun Yat-sen University
1991-01-01
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| Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
| Subjects: | |
| Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43593566/ |
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