Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkers

After the outbreak of the coronavirus disease (COVID-19), bio-sensing devices became very essential life-saving tools and showed a different perspective in the medical diagnostic field. Despite of all the advanced treatments in cancer, the early detection and diagnosing the first stage of the diseas...

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Main Authors: Keerthana Madhivanan, Raji Atchudan, Sandeep Arya, Ashok K. Sundramoorthy
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Oral Oncology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2772906024002097
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author Keerthana Madhivanan
Raji Atchudan
Sandeep Arya
Ashok K. Sundramoorthy
author_facet Keerthana Madhivanan
Raji Atchudan
Sandeep Arya
Ashok K. Sundramoorthy
author_sort Keerthana Madhivanan
collection DOAJ
description After the outbreak of the coronavirus disease (COVID-19), bio-sensing devices became very essential life-saving tools and showed a different perspective in the medical diagnostic field. Despite of all the advanced treatments in cancer, the early detection and diagnosing the first stage of the disease is very important. Over the last decade, the field-effect transistors (FETs) based biosensors have been demonstrated for the detection of various cancer biomarkers. FETs based biosensors were highly sensitive and selective compared to the other traditional sensing devices such as amplification-refractory mutations, Western blot, electrochemical, digital polymerase chain reaction and next generation sequencing methods. Moreover, FETs-based biosensors offer the early diagnosis of the disease with high specificity and high sensitivity at a relatively low cost.
format Article
id doaj-art-b1ec2d5225b84b71a0b8208d73108ba3
institution Kabale University
issn 2772-9060
language English
publishDate 2024-06-01
publisher Elsevier
record_format Article
series Oral Oncology Reports
spelling doaj-art-b1ec2d5225b84b71a0b8208d73108ba32025-01-09T06:15:57ZengElsevierOral Oncology Reports2772-90602024-06-0110100363Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkersKeerthana Madhivanan0Raji Atchudan1Sandeep Arya2Ashok K. Sundramoorthy3Centre for Nano-Biosensors, Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, Tamil Nadu, IndiaSchool of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Republic of KoreaDepartment of Physics, University of Jammu, Jammu, Jammu and Kashmir, 180006, IndiaCentre for Nano-Biosensors, Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, Tamil Nadu, India; Corresponding author.After the outbreak of the coronavirus disease (COVID-19), bio-sensing devices became very essential life-saving tools and showed a different perspective in the medical diagnostic field. Despite of all the advanced treatments in cancer, the early detection and diagnosing the first stage of the disease is very important. Over the last decade, the field-effect transistors (FETs) based biosensors have been demonstrated for the detection of various cancer biomarkers. FETs based biosensors were highly sensitive and selective compared to the other traditional sensing devices such as amplification-refractory mutations, Western blot, electrochemical, digital polymerase chain reaction and next generation sequencing methods. Moreover, FETs-based biosensors offer the early diagnosis of the disease with high specificity and high sensitivity at a relatively low cost.http://www.sciencedirect.com/science/article/pii/S2772906024002097
spellingShingle Keerthana Madhivanan
Raji Atchudan
Sandeep Arya
Ashok K. Sundramoorthy
Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkers
Oral Oncology Reports
title Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkers
title_full Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkers
title_fullStr Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkers
title_full_unstemmed Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkers
title_short Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkers
title_sort utilization of nanomaterials functionalized bio field effect transistors for detection of cancer biomarkers
url http://www.sciencedirect.com/science/article/pii/S2772906024002097
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AT sandeeparya utilizationofnanomaterialsfunctionalizedbiofieldeffecttransistorsfordetectionofcancerbiomarkers
AT ashokksundramoorthy utilizationofnanomaterialsfunctionalizedbiofieldeffecttransistorsfordetectionofcancerbiomarkers