Chromoblastomycosis mimicking Squamous Cell Carcinoma: a case report

Chromoblastomycosis (CM), a chronic subcutaneous mycosis, is caused by several dematiaceous fungi, the most common being Fonsecaea pedrosoi . It usually occurs in the lower extremities following traumatic implantation of the organisms. We are reporting a case of rapidly developing case of CM on the...

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Main Authors: BMM Kayastha, R Shrestha, Pan Shrestha, A Karki
Format: Article
Language:English
Published: Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) 2012-01-01
Series:Nepal Journal of Dermatology, Venereology & Leprology
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Online Access:https://www.nepjol.info/index.php/NJDVL/article/view/5714
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author BMM Kayastha
R Shrestha
Pan Shrestha
A Karki
author_facet BMM Kayastha
R Shrestha
Pan Shrestha
A Karki
author_sort BMM Kayastha
collection DOAJ
description Chromoblastomycosis (CM), a chronic subcutaneous mycosis, is caused by several dematiaceous fungi, the most common being Fonsecaea pedrosoi . It usually occurs in the lower extremities following traumatic implantation of the organisms. We are reporting a case of rapidly developing case of CM on the unilateral lower limb with a fungating mass like ulcerative lesion and hyperkeratotic warty growth. We could not explain the pattern of this rapid growth which seems to be one of the rare presentations. Scraping from a verrucous lesion in potassium hydroxide preparation revealed mycelia arising from sclerotic bodies The histopathology from the warty lesion showed granulomatous lesion without muriform or medlar bodies. The histopathology from the ulcerative lesion did not show any malignant changes. Our case responded very well to itraconazole. This case is presented here for the rapidity of growth and the development of a fungating mass and bleeding that simulated the behaviour of squamous cell carcinoma. DOI: http://dx.doi.org/10.3126/njdvl.v8i1.5714   Nepal Journal of Dermatology, Venereology & Leprology 8(1) 2009 22-26
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institution Kabale University
issn 2091-0231
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language English
publishDate 2012-01-01
publisher Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
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series Nepal Journal of Dermatology, Venereology & Leprology
spelling doaj-art-b182dc88358f440f9b2b78f3cbf8fbb22025-08-23T10:05:37ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2012-01-018110.3126/njdvl.v8i1.5714Chromoblastomycosis mimicking Squamous Cell Carcinoma: a case reportBMM Kayastha0R Shrestha1Pan Shrestha2A Karki3Associate Professor and Senior Consultant Dermatologist, Department of Dermatology and STD National Academy of Medical Sciences (NAMS), Bir Hospital, KathmanduResident, Department of Dermatology and STD National Academy of Medical Sciences (NAMS), Bir Hospital, KathmanduResident, Department of Dermatology and STD National Academy of Medical Sciences (NAMS), Bir Hospital, KathmanduResident, Department of Dermatology and STD National Academy of Medical Sciences (NAMS), Bir Hospital, Kathmandu Chromoblastomycosis (CM), a chronic subcutaneous mycosis, is caused by several dematiaceous fungi, the most common being Fonsecaea pedrosoi . It usually occurs in the lower extremities following traumatic implantation of the organisms. We are reporting a case of rapidly developing case of CM on the unilateral lower limb with a fungating mass like ulcerative lesion and hyperkeratotic warty growth. We could not explain the pattern of this rapid growth which seems to be one of the rare presentations. Scraping from a verrucous lesion in potassium hydroxide preparation revealed mycelia arising from sclerotic bodies The histopathology from the warty lesion showed granulomatous lesion without muriform or medlar bodies. The histopathology from the ulcerative lesion did not show any malignant changes. Our case responded very well to itraconazole. This case is presented here for the rapidity of growth and the development of a fungating mass and bleeding that simulated the behaviour of squamous cell carcinoma. DOI: http://dx.doi.org/10.3126/njdvl.v8i1.5714   Nepal Journal of Dermatology, Venereology & Leprology 8(1) 2009 22-26 https://www.nepjol.info/index.php/NJDVL/article/view/5714Chromoblastomycosis
spellingShingle BMM Kayastha
R Shrestha
Pan Shrestha
A Karki
Chromoblastomycosis mimicking Squamous Cell Carcinoma: a case report
Nepal Journal of Dermatology, Venereology & Leprology
Chromoblastomycosis
title Chromoblastomycosis mimicking Squamous Cell Carcinoma: a case report
title_full Chromoblastomycosis mimicking Squamous Cell Carcinoma: a case report
title_fullStr Chromoblastomycosis mimicking Squamous Cell Carcinoma: a case report
title_full_unstemmed Chromoblastomycosis mimicking Squamous Cell Carcinoma: a case report
title_short Chromoblastomycosis mimicking Squamous Cell Carcinoma: a case report
title_sort chromoblastomycosis mimicking squamous cell carcinoma a case report
topic Chromoblastomycosis
url https://www.nepjol.info/index.php/NJDVL/article/view/5714
work_keys_str_mv AT bmmkayastha chromoblastomycosismimickingsquamouscellcarcinomaacasereport
AT rshrestha chromoblastomycosismimickingsquamouscellcarcinomaacasereport
AT panshrestha chromoblastomycosismimickingsquamouscellcarcinomaacasereport
AT akarki chromoblastomycosismimickingsquamouscellcarcinomaacasereport