5-Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan as a Potential Standard for Second-line Therapy in Extrapulmonary Neuroendocrine Carcinomas

5-Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan as a Potential Standard for Second-line Therapy in Extrapulmonary Neuroendocrine Carcinomas

Background: Neuroendocrine carcinomas (NECs) are classified by the World Health Organization as poorly differentiated, aggressive Grade 3 tumors with high proliferative indices and frequent lung involvement. While initial treatment for advanced NEC typically involves etoposide and platinum-based the...

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Bibliographic Details
Main Authors: I-Wei Ho, Nai-Jung Chiang, Jiun-I Lai, Peter Mu-Hsin Chang, San-Chi Chen, Yi-Ping Hung, Ming-Huang Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Cancer Research and Practice
Subjects:
extrapulmonary
5-fluorouracil
leucovorin
and irinotecan
oxaliplatin
second-line therapy
ipilimumab
neuroendocrine carcinoma
neuroendocrine carcinomas
nivolumab
Online Access:https://journals.lww.com/10.4103/ejcrp.eJCRP-D-24-00032
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