Royal Jelly and 10-Hydroxy-2-Decenoic acid activate autophagy through mTOR/ULK1 pathway to improve cognitive function in diabetic mice

Royal Jelly and 10-Hydroxy-2-Decenoic acid activate autophagy through mTOR/ULK1 pathway to improve cognitive function in diabetic mice

Diabetes, a ruthless chronic metabolic disorder, is increasingly considered to jeopardize global well-being over the decades. Royal jelly (RJ) is a complex natural product secreted by worker bees containing a unique fatty acid known as 10-hydroxy-2-decenoic acid (10-HDA). This study aimed to verify...

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Bibliographic Details
Main Authors: Lu Xiu, Rongguang Ge, Siyu Lu, Linwei Li, Wenqi Huang, Guojun Du, Zengli Zhang, Jie Zhang, Zhongxiao Wan, Jie Chang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Functional Foods
Subjects:
Autophagy
Cognitive dysfunction
Diabetes
Royal Jelly
10-HDA
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624006522
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