Systemic immune-inflammatory biomarkers combined with the CRP-albumin-lymphocyte index predict surgical site infection following posterior lumbar spinal fusion: a retrospective study using machine learning

Systemic immune-inflammatory biomarkers combined with the CRP-albumin-lymphocyte index predict surgical site infection following posterior lumbar spinal fusion: a retrospective study using machine learning

ObjectivesEmerging systemic immune-inflammatory biomarkers demonstrate potential for predicting postoperative complications. This study develops machine learning models to assess the combined predictive value of Aggregate Index of Systemic Inflammation (AISI), Systemic Immune-Inflammation Index (SII...

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Bibliographic Details
Main Authors: Zixiang Pang, Jiawei Liang, Jiayi Chen, Yangqin Ou, Qinmian Wu, Shengsheng Huang, Shengbin Huang, Yuanming Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
Subjects:
systemic immune-inflammation biomarkers
CRP-albumin-lymphocyte index
surgical site infection
machine learning
retrospective study
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1590248/full
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