Fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in Qatar
Introduction: This study was conducted at Hamad General Hospital to determine the incidence of fungal peritonitis and to describe its clinical and microbiological findings in patients undergoing continuous ambulatory peritoneal dialysis in Qatar. Methodology: The medical records of these patients...
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The Journal of Infection in Developing Countries
2011-07-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/1519 |
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| author | Fahmi Yousef Khan Mohammed Elsayed Deshmukh Anand Mohammed Abu Khattab Doiphode Sanjay |
| author_facet | Fahmi Yousef Khan Mohammed Elsayed Deshmukh Anand Mohammed Abu Khattab Doiphode Sanjay |
| author_sort | Fahmi Yousef Khan |
| collection | DOAJ |
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Introduction: This study was conducted at Hamad General Hospital to determine the incidence of fungal peritonitis and to describe its clinical and microbiological findings in patients undergoing continuous ambulatory peritoneal dialysis in Qatar.
Methodology: The medical records of these patients between 1 January 2005 and 31 December 2008 were retrospectively reviewed and the collected data were analysed.
Results: During the study period, 141 episodes of peritonitis were observed among 294 patients. In 14 of these episodes (9.9%), fungal peritonitis was reported in 14 patients with a rate of 0.05 episodes per patient year, while the bacterial peritonitis rate was 0.63 per patient year. Thirteen (93%) patients had one or more previous episodes of bacterial peritonitis that was treated with multiple broad-spectrum antibiotics, 11 (85%) had received broad-spectrum antibiotics within the preceding month, 12 (92%) within three months, and 8 (62%) within six months. Candida species were the only fungal species isolated from the dialysate with predominance of non-albicans Candida species (especially Candida parapsilosis). Therapeutic approach was immediate catheter removal, followed by systemic antifungal therapy and temporary haemodialysis. Nine patients (64.3%) were continued on haemodialysis, whereas five patients (35.7%) died.
Conclusions: Prior antibiotic use was an important risk factor predisposing patients to the development of fungal peritonitis. Early detection of fungal peritonitis would lead to early institution of appropriate therapy and prevention of complications.
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| format | Article |
| id | doaj-art-b0e5daeda03f4881b59c0c5d0f3e1e07 |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2011-07-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-b0e5daeda03f4881b59c0c5d0f3e1e072025-08-20T03:48:58ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802011-07-0150910.3855/jidc.1519Fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in QatarFahmi Yousef Khan0Mohammed Elsayed1Deshmukh Anand2Mohammed Abu Khattab3Doiphode Sanjay4Hamad General Hospital, Doha, QatarHamad General Hospital, Doha, QatarHamad General Hospital, Doha, QatarHamad General Hospital, Doha, QatarHamad General Hospital, Doha, Qatar Introduction: This study was conducted at Hamad General Hospital to determine the incidence of fungal peritonitis and to describe its clinical and microbiological findings in patients undergoing continuous ambulatory peritoneal dialysis in Qatar. Methodology: The medical records of these patients between 1 January 2005 and 31 December 2008 were retrospectively reviewed and the collected data were analysed. Results: During the study period, 141 episodes of peritonitis were observed among 294 patients. In 14 of these episodes (9.9%), fungal peritonitis was reported in 14 patients with a rate of 0.05 episodes per patient year, while the bacterial peritonitis rate was 0.63 per patient year. Thirteen (93%) patients had one or more previous episodes of bacterial peritonitis that was treated with multiple broad-spectrum antibiotics, 11 (85%) had received broad-spectrum antibiotics within the preceding month, 12 (92%) within three months, and 8 (62%) within six months. Candida species were the only fungal species isolated from the dialysate with predominance of non-albicans Candida species (especially Candida parapsilosis). Therapeutic approach was immediate catheter removal, followed by systemic antifungal therapy and temporary haemodialysis. Nine patients (64.3%) were continued on haemodialysis, whereas five patients (35.7%) died. Conclusions: Prior antibiotic use was an important risk factor predisposing patients to the development of fungal peritonitis. Early detection of fungal peritonitis would lead to early institution of appropriate therapy and prevention of complications. https://jidc.org/index.php/journal/article/view/1519amphotericin BCAPDCandida parapsilosisfungal peritonitisfluconazole |
| spellingShingle | Fahmi Yousef Khan Mohammed Elsayed Deshmukh Anand Mohammed Abu Khattab Doiphode Sanjay Fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in Qatar Journal of Infection in Developing Countries amphotericin B CAPD Candida parapsilosis fungal peritonitis fluconazole |
| title | Fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in Qatar |
| title_full | Fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in Qatar |
| title_fullStr | Fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in Qatar |
| title_full_unstemmed | Fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in Qatar |
| title_short | Fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in Qatar |
| title_sort | fungal peritonitis in patients undergoing continuous ambulatory peritoneal dialysis in qatar |
| topic | amphotericin B CAPD Candida parapsilosis fungal peritonitis fluconazole |
| url | https://jidc.org/index.php/journal/article/view/1519 |
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