Surgery-induced neuroinflammatory transcriptional programs in medial prefrontal cortex of mice during early phase of perioperative neurocognitive disorders

Surgery-induced neuroinflammatory transcriptional programs in medial prefrontal cortex of mice during early phase of perioperative neurocognitive disorders

Patients receiving anesthesia and surgery may experience cognitive dysfunction, memory deficits, and mental disturbances, which are referred to as perioperative neurocognitive disorders (PND). The function of the medial prefrontal cortex (mPFC) is disrupted during early phase of PND. To gain insight...

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Bibliographic Details
Main Authors: Xiaodong Tang, Xuwu Xiang, Yang Yu, Shuyuan Huang, Caifei Pan, Shuyuan Gan, Yongxing Yao
Format: Article
Language:English
Published: PeerJ Inc. 2024-12-01
Series:PeerJ
Subjects:
Surgery
Cognitive dysfunction
RNA sequencing
Neuroinflammation
Medial prefrontal cortex
Online Access:https://peerj.com/articles/18664.pdf
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