SYNTHESIS, MOLECULAR DOCKING, DYNAMICS ANALYSIS STUDIES, AND CYTOTOXICITYACTIVITY EVALUATION OF NOVEL BERBERINE DERIVATIVE BEARING OXADIAZOLE AND o-DIAMINOBENZENE MOIETIES
Berberine represents a prominent compound with commendable antitumor activity, a novel berberine derivative with substituted o-diaminobenzene moiety linked at the 9-position through oxadiazole and alkyl chain is designed, synthesized by reference to the histone deacetylase (HDAC) inhibitor structure...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Química
2025-05-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422025000500305&lng=en&tlng=en |
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