Impact of polygenic risk score (PRS) for coronary artery disease on physician decision-making and patient care

Impact of polygenic risk score (PRS) for coronary artery disease on physician decision-making and patient care

IntroductionPolygenic risk scores (PRS) have emerged as a promising tool for refining cardiovascular risk prediction, yet their real-world impact on physician decision-making remains unclear. This study aimed to evaluate how the integration of a coronary artery disease (CAD) PRS with traditional cli...

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Bibliographic Details
Main Authors: Georgios Ntritsos, Erez Ornan, Nir Gamliel, Gil Chernin, Arnold Pallay, Michael Chen, Efi Kessous, Eran Feldhay
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Genetics
Subjects:
polygenic risk score (PRS)
coronary artery disease (CAD)
cardiovascular risk assessment
personalized medicine
genetic risk stratification
clinical decision-making
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1625822/full
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https://www.frontiersin.org/articles/10.3389/fgene.2025.1625822/full

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