The research of pharmacokinetic parameters and metabolism of sodium 2-((4-amino-5-(thiophen-2-ylmethyl)-4h-1,2,4-triazol-3-yl)thio)acetate for use in military and civilian medicine

The research of pharmacokinetic parameters and metabolism of sodium 2-((4-amino-5-(thiophen-2-ylmethyl)-4h-1,2,4-triazol-3-yl)thio)acetate for use in military and civilian medicine

Introduction. Chromatographic methods are often used in the study of pharmacokinetic parameters. Thus, the aim of the study was to investigate the pharmacokinetic parameters and metabolism of sodium 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetate (ASP) as a potential active p...

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Bibliographic Details
Main Authors: D. L. Usenko, B. O. Varynskyi, O. I. Panasenko, L. P. Morozova, O. P. Shmatenko, A. M. Solomennyi
Format: Article
Language:English
Published: Ukrainian Military Medical Academy 2024-12-01
Series:Український журнал військової медицини
Subjects:
1,2,4-triazole, HPLC-MS, metabolism, biotransformation prediction.
Online Access:https://ujmm.org.ua/index.php/journal/article/view/497
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