Identification and Characterization of Two Aryl Sulfotransferases from Deep-Sea Marine Fungi and Their Implications in the Sulfation of Secondary Metabolites

Identification and Characterization of Two Aryl Sulfotransferases from Deep-Sea Marine Fungi and Their Implications in the Sulfation of Secondary Metabolites

Sulfation plays a critical role in the biosynthesis of small molecules, regulatory mechanisms such as hormone signaling, and detoxification processes (phase II enzymes). The sulfation reaction is catalyzed by a broad family of enzymes known as sulfotransferases (SULTs), which have been extensively s...

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Bibliographic Details
Main Authors: Nicolas Graziano, Beatriz Arce-López, Tristan Barbeyron, Ludovic Delage, Elise Gerometta, Catherine Roullier, Gaëtan Burgaud, Elisabeth Poirier, Laure Martinelli, Jean-Luc Jany, Nolwenn Hymery, Laurence Meslet-Cladiere
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Marine Drugs
Subjects:
marine fungi
enzymatic sulfation
sulfated metabolites
sulfotransferases
cytotoxic activity
sulfated mycotoxin
Online Access:https://www.mdpi.com/1660-3397/22/12/572
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