Plasma pQTL and brain eQTL integration identifies PNKP as a therapeutic target and reveals mechanistic insights into migraine pathophysiology

Abstract Background Migraine is a prevalent neurological disorder affecting 14.1% of the global population. Despite advances in genetic research, further investigation is needed to identify therapeutic targets and better understand its mechanisms. In this study, we aimed to identify drug targets and...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiafei Lou, Miaoqian Tu, Maosheng Xu, Zhijian Cao, Wenwen Song
Format: Article
Language:English
Published: BMC 2024-11-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:https://doi.org/10.1186/s10194-024-01922-z
Tags: Add Tag
No Tags, Be the first to tag this record!