Transcriptional profiling of Chlamydia trachomatis and its host in an ex vivo endocervical primary cell culture system using dual RNA sequencing

Transcriptional profiling of Chlamydia trachomatis and its host in an ex vivo endocervical primary cell culture system using dual RNA sequencing

Chlamydia trachomatis (Ct) is an obligate intracellular bacterium that causes significant ocular and urogenital morbidity worldwide. Understanding host-pathogen interactions is challenging but dual RNA sequencing offers simultaneous transcriptome data for comprehensive interrogations into these inte...

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Bibliographic Details
Main Authors: Olusola Olagoke, Siddharth Chittaranjan, Deborah Dean
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Chlamydia trachomatis
dual RNA sequencing
primary endocervical stromal cells
chlamydial pathogenesis
host pathogen environment interactions
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1613922/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1613922/full

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