Association between sleep disorders and myopia in Shanghai adolescents: a cross-sectional survey conducted among junior school students

Abstract Background Numerous research suggest that longer sleep duration correlates with a reduced likelihood of myopia onset in adolescents. Does total sleep quality influence myopia? This study aims to examine the relationship between sleep disorders in adolescents and their effects on myopia and...

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Main Authors: Xiaoya Yin, Xuelai Wang, Zhe Zhang, Yani Zhai, Xinyi Zhou, Linlin Yuan, Shuman Li, Zhengzhong Wang, Lijing Sun, Chunyan Luo
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Ophthalmology
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Online Access:https://doi.org/10.1186/s12886-025-03994-0
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Summary:Abstract Background Numerous research suggest that longer sleep duration correlates with a reduced likelihood of myopia onset in adolescents. Does total sleep quality influence myopia? This study aims to examine the relationship between sleep disorders in adolescents and their effects on myopia and the risk of acquiring high myopia. Methods Data from second-grade middle school students across 16 districts in Shanghai were studied. A total of 2,337 valid observations collected. Two study samples were established: the entire student population and students diagnosed with myopia. Propensity score matching (PSM) was conducted to equilibrate the confounding variables between the sleep disorder and non-sleep disorder groups in each sample. Odds ratios (OR) were computed to assess the effect size. A generalized additive model was used to analyze the relationship between SE and sleep disorder. Results Prior to PSM, the likelihood of myopia among students was significantly correlated with a higher prevalence of sleep disorders (OR = 1.40, 95%CI: 1.02–1.91). but this significance diminished after matching (OR = 1.24, 95%CI: 0.82–1.85). In the examination of myopic students, before to PSM, sleep disorders were recognized as a potential risk factor for high myopia. Nonetheless, this correlation did not reach statistical significance (OR = 1.21; 95%CI:0.80–1.84). Comparable outcomes were achieved after the matching process (OR = 1.08; 95%CI:0.62–1.87). The modelling outcomes of the generalized additive model also revealed no correlation between sleep disrder and myopia or high myopia. Conclusion This study found no significant correlation between myopia or high myopia and sleep disorder. However, the residual effect sizes post-PSM still indicate potential biological interactions.
ISSN:1471-2415