Neutrophils Respond Selectively to Physical Cues: Roughness Modulates Its Granule Release, and NETosis

Neutrophils Respond Selectively to Physical Cues: Roughness Modulates Its Granule Release, and NETosis

Our study examined how different titanium alloy Ti6Al4V (Ti64) and zirconia (ZrO<sub>2</sub>) surfaces, ranging from rough to very smooth, affect the expression of elastase (NE), matrix metalloproteinase (MMP)-8, MMP-9, and extracellular traps (NETs) by neutrophils. Discs of Ti64 and ZrO...

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Bibliographic Details
Main Authors: Gayathiri Elangovan, Daniel J. Fernandes, Andrew Cameron, Souptik Basu, Joao Martins De Mello Neto, Peishan Jiang, Peter Reher, Stephen Hamlet, Carlos Marcelo S. Figueredo
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Functional Biomaterials
Subjects:
neutrophils
titanium oxide
zirconia
roughness
Online Access:https://www.mdpi.com/2079-4983/15/11/342
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