Genome-wide DNA methylation analysis reveals a unique methylation pattern for pleural mesothelioma compared to healthy pleura and other lung diseases

Genome-wide DNA methylation analysis reveals a unique methylation pattern for pleural mesothelioma compared to healthy pleura and other lung diseases

Abstract Background Pleural mesothelioma (PM) is a rare and aggressive cancer type, typically diagnosed at advanced stages. Distinguishing PM from other lung diseases is often challenging. There is an urgent need for biomarkers that can enable early detection. Interest in the field of epigenetics ha...

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Main Authors: Janah Vandenhoeck, Joe Ibrahim, Nele De Meulenaere, Dieter Peeters, Jo Raskin, Jeroen M. H. Hendriks, Paul Van Schil, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Clinical Epigenetics
Subjects:
Epigenetics
DNA methylation
Pleural mesothelioma
Lung cancer
Healthy pleura
Online Access:https://doi.org/10.1186/s13148-024-01790-z
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https://doi.org/10.1186/s13148-024-01790-z

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