Fertility preservation counselling and practice among women with lymphomas: a retrospective study
Background Research on fertility preservation among women diagnosed with lymphoma is very limited. We aimed to assess the receipt of fertility preservation information and use of fertility preservation among women diagnosed with lymphoma.Methods This was a retrospective, single-centre study. Patient...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Journal of Obstetrics and Gynaecology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/01443615.2025.2449679 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841527848513306624 |
|---|---|
| author | Mariola Hernández Martínez César Lizán Tudela Blanca Carreras Gamón Laura Gregori Navarro |
| author_facet | Mariola Hernández Martínez César Lizán Tudela Blanca Carreras Gamón Laura Gregori Navarro |
| author_sort | Mariola Hernández Martínez |
| collection | DOAJ |
| description | Background Research on fertility preservation among women diagnosed with lymphoma is very limited. We aimed to assess the receipt of fertility preservation information and use of fertility preservation among women diagnosed with lymphoma.Methods This was a retrospective, single-centre study. Patients with Hodgkin and non-Hodgkin lymphoma were screened from the electronic medical records of individuals who attended the Haematology Department at the study site between 2000 and 2018 and were followed-up for obstetric outcomes and onset of menopause until December 2023.Results Forty-three patients had available electronic health records. Overall, 13 (36.1%) of the 36 patients ≤45 years old received fertility preservation counselling; it was more frequent among nulliparous women (11/23, 47.8%), women aged ≤35 years (11/26, 42.3%), and those diagnosed in the latest study period from 2015 to 2018 (9/16, 56.3%). Of the 13 patients who were informed about fertility preservation, 2 patients refused this intervention, and fertility preservation was contraindicated for 3 patients, leading to a total of eight women who underwent fertility preservation strategies: six underwent ovarian cortex cryopreservation, and two underwent oocyte vitrification. Among the participants aged ≤45 years, 10 (27.8%) had at least one live birth after diagnosis. Fifteen (34.9%) of the 43 participants exhibited amenorrhoea after the initiation of chemotherapy, including 4 women ≤35 years of age. The median (range) age at menopause in this series was 45 (27-50) years.Conclusion Even though the situation appears to have improved in recent years, we are far from reaching the target of all women with lymphoma who are of reproductive age receiving fertility preservation counselling before initiating chemotherapy. |
| format | Article |
| id | doaj-art-ae6c1feffda8496c95a155237120e542 |
| institution | Kabale University |
| issn | 0144-3615 1364-6893 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Obstetrics and Gynaecology |
| spelling | doaj-art-ae6c1feffda8496c95a155237120e5422025-01-15T08:00:29ZengTaylor & Francis GroupJournal of Obstetrics and Gynaecology0144-36151364-68932025-12-0145110.1080/01443615.2025.2449679Fertility preservation counselling and practice among women with lymphomas: a retrospective studyMariola Hernández Martínez0César Lizán Tudela1Blanca Carreras Gamón2Laura Gregori Navarro3Department of Pediatrics, Obstetrics and Gynecology, Universitat de Valencia, Valencia, SpainDepartment of Pediatrics, Obstetrics and Gynecology, Universitat de Valencia, Valencia, SpainDepartment of Pediatrics, Obstetrics and Gynecology, Universitat de Valencia, Valencia, SpainDepartment of Pediatrics, Obstetrics and Gynecology, Universitat de Valencia, Valencia, SpainBackground Research on fertility preservation among women diagnosed with lymphoma is very limited. We aimed to assess the receipt of fertility preservation information and use of fertility preservation among women diagnosed with lymphoma.Methods This was a retrospective, single-centre study. Patients with Hodgkin and non-Hodgkin lymphoma were screened from the electronic medical records of individuals who attended the Haematology Department at the study site between 2000 and 2018 and were followed-up for obstetric outcomes and onset of menopause until December 2023.Results Forty-three patients had available electronic health records. Overall, 13 (36.1%) of the 36 patients ≤45 years old received fertility preservation counselling; it was more frequent among nulliparous women (11/23, 47.8%), women aged ≤35 years (11/26, 42.3%), and those diagnosed in the latest study period from 2015 to 2018 (9/16, 56.3%). Of the 13 patients who were informed about fertility preservation, 2 patients refused this intervention, and fertility preservation was contraindicated for 3 patients, leading to a total of eight women who underwent fertility preservation strategies: six underwent ovarian cortex cryopreservation, and two underwent oocyte vitrification. Among the participants aged ≤45 years, 10 (27.8%) had at least one live birth after diagnosis. Fifteen (34.9%) of the 43 participants exhibited amenorrhoea after the initiation of chemotherapy, including 4 women ≤35 years of age. The median (range) age at menopause in this series was 45 (27-50) years.Conclusion Even though the situation appears to have improved in recent years, we are far from reaching the target of all women with lymphoma who are of reproductive age receiving fertility preservation counselling before initiating chemotherapy.https://www.tandfonline.com/doi/10.1080/01443615.2025.2449679Cancerchemotherapycounsellingfertility preservationlive birth ratelymphoma |
| spellingShingle | Mariola Hernández Martínez César Lizán Tudela Blanca Carreras Gamón Laura Gregori Navarro Fertility preservation counselling and practice among women with lymphomas: a retrospective study Journal of Obstetrics and Gynaecology Cancer chemotherapy counselling fertility preservation live birth rate lymphoma |
| title | Fertility preservation counselling and practice among women with lymphomas: a retrospective study |
| title_full | Fertility preservation counselling and practice among women with lymphomas: a retrospective study |
| title_fullStr | Fertility preservation counselling and practice among women with lymphomas: a retrospective study |
| title_full_unstemmed | Fertility preservation counselling and practice among women with lymphomas: a retrospective study |
| title_short | Fertility preservation counselling and practice among women with lymphomas: a retrospective study |
| title_sort | fertility preservation counselling and practice among women with lymphomas a retrospective study |
| topic | Cancer chemotherapy counselling fertility preservation live birth rate lymphoma |
| url | https://www.tandfonline.com/doi/10.1080/01443615.2025.2449679 |
| work_keys_str_mv | AT mariolahernandezmartinez fertilitypreservationcounsellingandpracticeamongwomenwithlymphomasaretrospectivestudy AT cesarlizantudela fertilitypreservationcounsellingandpracticeamongwomenwithlymphomasaretrospectivestudy AT blancacarrerasgamon fertilitypreservationcounsellingandpracticeamongwomenwithlymphomasaretrospectivestudy AT lauragregorinavarro fertilitypreservationcounsellingandpracticeamongwomenwithlymphomasaretrospectivestudy |