The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression
Abstract The Hippo signaling pathway controls organ size and tumorigenesis through a kinase cascade that inactivates Yes‐associated protein (YAP). Here, we show that YAP plays a central role in controlling the progression of cervical cancer. Our results suggest that YAP expression is associated with...
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| Main Authors: | Chunbo He, Dagan Mao, Guohua Hua, Xiangmin Lv, Xingcheng Chen, Peter C Angeletti, Jixin Dong, Steven W Remmenga, Kerry J Rodabaugh, Jin Zhou, Paul F Lambert, Peixin Yang, John S Davis, Cheng Wang |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2015-09-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201404976 |
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