The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

Abstract The Hippo signaling pathway controls organ size and tumorigenesis through a kinase cascade that inactivates Yes‐associated protein (YAP). Here, we show that YAP plays a central role in controlling the progression of cervical cancer. Our results suggest that YAP expression is associated with...

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Main Authors: Chunbo He, Dagan Mao, Guohua Hua, Xiangmin Lv, Xingcheng Chen, Peter C Angeletti, Jixin Dong, Steven W Remmenga, Kerry J Rodabaugh, Jin Zhou, Paul F Lambert, Peixin Yang, John S Davis, Cheng Wang
Format: Article
Language:English
Published: Springer Nature 2015-09-01
Series:EMBO Molecular Medicine
Subjects:
cervical cancer
EGFR
Hippo
HPV
YAP
Online Access:https://doi.org/10.15252/emmm.201404976
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https://doi.org/10.15252/emmm.201404976

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