Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration

Abstract Macrophages play a crucial role in coordinating the skeletal muscle repair response, but their phenotypic diversity and the transition of specialized subsets to resolution-phase macrophages remain poorly understood. Here, to address this issue, we induced injury and performed single-cell RN...

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Main Authors: Yu-Fan Chen, Chien-Wei Lee, Yi-Shuan J. Li, Wei-Ting Lin, Hsiao-Yun Chen, Yu-Chuan Chen, Chia-Hao Lin, Jennifer Hui-Chun Ho, Li-Fan Lu, Shu Chien, Oscar Kuang-Sheng Lee
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01467-4
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