Advances in Radiation/Photon therapy technology for the treatment of brain metastases
With advancements in systemic therapy, the incidence of brain metastases (BMs) continues to rise, leading to severe neurological complications. Effective and precise treatment modalities are, therefore, critically important for managing BMs. Radiation therapy (RT), including photon therapy, has been...
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2025-07-01
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| Series: | Journal of Innovative Optical Health Sciences |
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| Online Access: | https://www.worldscientific.com/doi/10.1142/S1793545825300058 |
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| author | Hui Wang Jing Chu Yao Ren Wenfan Deng Lidan Zhang Lijuan Shen Yu Kuang Lixia Xu |
| author_facet | Hui Wang Jing Chu Yao Ren Wenfan Deng Lidan Zhang Lijuan Shen Yu Kuang Lixia Xu |
| author_sort | Hui Wang |
| collection | DOAJ |
| description | With advancements in systemic therapy, the incidence of brain metastases (BMs) continues to rise, leading to severe neurological complications. Effective and precise treatment modalities are, therefore, critically important for managing BMs. Radiation therapy (RT), including photon therapy, has been essential in managing BMs. Recent technological advances have significantly enhanced the precision, efficacy, and safety of these treatments. This comprehensive review provides an in-depth examination of the latest advancements in radiation and photon therapy technologies for treating BMs, focusing on innovations such as stereotactic radiosurgery (SRS), whole-brain radiation therapy (WBRT), laser interstitial thermal therapy (LITT), and other radiation-related treatment modalities. Additionally, we discuss clinical outcomes, challenges, and future directions in this rapidly evolving field. While a detailed comparison of techniques is beyond the scope of this paper, this paper provides up-to-date technical information for physicians, medical physicists, patients, and researchers in related fields, potentially enhancing clinical outcomes. Among the treatment modalities, SRS has become a cornerstone of RT for BMs, with its implementation spanning multiple modalities over the past few decades. Given its inherent minimally invasive nature and growing clinical acceptance, SRS is positioned to further evolve as a key therapeutic tool in both neurosurgery and radiotherapy. |
| format | Article |
| id | doaj-art-ad6b807720e0430f802a44afd76e6a0c |
| institution | Kabale University |
| issn | 1793-5458 1793-7205 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Journal of Innovative Optical Health Sciences |
| spelling | doaj-art-ad6b807720e0430f802a44afd76e6a0c2025-08-20T03:48:27ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052025-07-01180410.1142/S1793545825300058Advances in Radiation/Photon therapy technology for the treatment of brain metastasesHui Wang0Jing Chu1Yao Ren2Wenfan Deng3Lidan Zhang4Lijuan Shen5Yu Kuang6Lixia Xu7Medical Imaging and Translational Medicine Laboratory, Department of Radiotherapy, Affiliated Hangzhou Cancer Hospital, Westlake University School of Medicine, Hangzhou 310002, P. R. ChinaSchool of Automation, Xi’an University of Posts and Telecommunications, Xi’an 710121, P. R. ChinaMedical Imaging and Translational Medicine Laboratory, Department of Radiotherapy, Affiliated Hangzhou Cancer Hospital, Westlake University School of Medicine, Hangzhou 310002, P. R. ChinaMedical Imaging and Translational Medicine Laboratory, Department of Radiotherapy, Affiliated Hangzhou Cancer Hospital, Westlake University School of Medicine, Hangzhou 310002, P. R. ChinaMedical Imaging and Translational Medicine Laboratory, Department of Radiotherapy, Affiliated Hangzhou Cancer Hospital, Westlake University School of Medicine, Hangzhou 310002, P. R. ChinaMedical Imaging and Translational Medicine Laboratory, Department of Radiotherapy, Affiliated Hangzhou Cancer Hospital, Westlake University School of Medicine, Hangzhou 310002, P. R. ChinaMedical Physics Program, University of Nevada, Las Vegas, NV 89154, USAMedical Imaging and Translational Medicine Laboratory, Department of Radiotherapy, Affiliated Hangzhou Cancer Hospital, Westlake University School of Medicine, Hangzhou 310002, P. R. ChinaWith advancements in systemic therapy, the incidence of brain metastases (BMs) continues to rise, leading to severe neurological complications. Effective and precise treatment modalities are, therefore, critically important for managing BMs. Radiation therapy (RT), including photon therapy, has been essential in managing BMs. Recent technological advances have significantly enhanced the precision, efficacy, and safety of these treatments. This comprehensive review provides an in-depth examination of the latest advancements in radiation and photon therapy technologies for treating BMs, focusing on innovations such as stereotactic radiosurgery (SRS), whole-brain radiation therapy (WBRT), laser interstitial thermal therapy (LITT), and other radiation-related treatment modalities. Additionally, we discuss clinical outcomes, challenges, and future directions in this rapidly evolving field. While a detailed comparison of techniques is beyond the scope of this paper, this paper provides up-to-date technical information for physicians, medical physicists, patients, and researchers in related fields, potentially enhancing clinical outcomes. Among the treatment modalities, SRS has become a cornerstone of RT for BMs, with its implementation spanning multiple modalities over the past few decades. Given its inherent minimally invasive nature and growing clinical acceptance, SRS is positioned to further evolve as a key therapeutic tool in both neurosurgery and radiotherapy.https://www.worldscientific.com/doi/10.1142/S1793545825300058Brain metastasesradiation therapystereotactic radiosurgerylaser interstitial thermal therapy |
| spellingShingle | Hui Wang Jing Chu Yao Ren Wenfan Deng Lidan Zhang Lijuan Shen Yu Kuang Lixia Xu Advances in Radiation/Photon therapy technology for the treatment of brain metastases Journal of Innovative Optical Health Sciences Brain metastases radiation therapy stereotactic radiosurgery laser interstitial thermal therapy |
| title | Advances in Radiation/Photon therapy technology for the treatment of brain metastases |
| title_full | Advances in Radiation/Photon therapy technology for the treatment of brain metastases |
| title_fullStr | Advances in Radiation/Photon therapy technology for the treatment of brain metastases |
| title_full_unstemmed | Advances in Radiation/Photon therapy technology for the treatment of brain metastases |
| title_short | Advances in Radiation/Photon therapy technology for the treatment of brain metastases |
| title_sort | advances in radiation photon therapy technology for the treatment of brain metastases |
| topic | Brain metastases radiation therapy stereotactic radiosurgery laser interstitial thermal therapy |
| url | https://www.worldscientific.com/doi/10.1142/S1793545825300058 |
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