Design, synthesis and bioactivity evaluation of phosphinanes as potential anticancer agents

Abstract The development of novel anticancer agents is crucial to the ongoing effort to combat cancer. In this study, six-membered phosphorus heterocycles (phosphinanes) were designed, synthesized, and evaluated as potential antiproliferative agents. A series of novel phosphinane derivatives was obt...

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Bibliographic Details
Main Authors: Elżbieta Łastawiecka, Paulina Strzyga-Łach, Ewelina Kiernozek-Kalińska, Marta Struga, Anna Bielenica
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-10692-w
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