Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin

Gastrointestinal metastases from cutaneous melanoma are rare and usually asymptomatic, with most patients not being clinically diagnosed throughout their lifetime. We report a case of how melanoma may metastasize insidiously in the small bowel. Unexplained iron deficiency anemia was assumed to be th...

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Main Authors: Cornelia Nitipir, Andreea Parosanu, Cristina Orlov-Slavu, Cătălin Piriianu, Radu Vrabie, Iulian Slavu, Valentin Calu
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Journal of Mind and Medical Sciences
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Online Access:https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1324&context=jmms
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author Cornelia Nitipir
Andreea Parosanu
Cristina Orlov-Slavu
Cătălin Piriianu
Radu Vrabie
Iulian Slavu
Valentin Calu
author_facet Cornelia Nitipir
Andreea Parosanu
Cristina Orlov-Slavu
Cătălin Piriianu
Radu Vrabie
Iulian Slavu
Valentin Calu
author_sort Cornelia Nitipir
collection DOAJ
description Gastrointestinal metastases from cutaneous melanoma are rare and usually asymptomatic, with most patients not being clinically diagnosed throughout their lifetime. We report a case of how melanoma may metastasize insidiously in the small bowel. Unexplained iron deficiency anemia was assumed to be the result of underlying gastrointestinal bleeding. Therefore, the diagnosis of jejunal metastasis from cutaneous melanoma was suggested based on imaging findings and made through the histopathological examination. According to the international guidelines, the patient underwent the complete excision of the primary tumor and therapeutic lymph node dissection. Furthermore, an adjuvant treatment was required to reduce the risk of recurrence. Both immunotherapy and surgical therapy have been shown to be effective, providing long-term survival in this case.
format Article
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institution Kabale University
issn 2392-7674
language English
publishDate 2022-04-01
publisher MDPI AG
record_format Article
series Journal of Mind and Medical Sciences
spelling doaj-art-ac9da1d4b68e497599b60f3ed986f3a52025-08-20T03:48:37ZengMDPI AGJournal of Mind and Medical Sciences2392-76742022-04-019118719210.22543/7674.91.P187192Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain originCornelia Nitipir0Andreea Parosanu1Cristina Orlov-Slavu2Cătălin Piriianu3Radu Vrabie4Iulian Slavu5Valentin Calu6CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, DEPARTMENT OF ONCOLOGY, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, DEPARTMENT OF ONCOLOGY, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, DEPARTMENT OF ONCOLOGY, BUCHAREST, ROMANIAELIAS UNIVERSITY EMERGENCY HOSPITAL, DEPARTMENT OF GENERAL SURGERY, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, DEPARTMENT OF ONCOLOGY, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, DEPARTMENT OF HUMAN ANATOMY, BUCHAREST, ROMANIAELIAS UNIVERSITY EMERGENCY HOSPITAL, DEPARTMENT OF GENERAL SURGERY, BUCHAREST, ROMANIAGastrointestinal metastases from cutaneous melanoma are rare and usually asymptomatic, with most patients not being clinically diagnosed throughout their lifetime. We report a case of how melanoma may metastasize insidiously in the small bowel. Unexplained iron deficiency anemia was assumed to be the result of underlying gastrointestinal bleeding. Therefore, the diagnosis of jejunal metastasis from cutaneous melanoma was suggested based on imaging findings and made through the histopathological examination. According to the international guidelines, the patient underwent the complete excision of the primary tumor and therapeutic lymph node dissection. Furthermore, an adjuvant treatment was required to reduce the risk of recurrence. Both immunotherapy and surgical therapy have been shown to be effective, providing long-term survival in this case. https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1324&context=jmmsjejunal metastasismelanomaanemiaimmune checkpoint inhibitors
spellingShingle Cornelia Nitipir
Andreea Parosanu
Cristina Orlov-Slavu
Cătălin Piriianu
Radu Vrabie
Iulian Slavu
Valentin Calu
Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin
Journal of Mind and Medical Sciences
jejunal metastasis
melanoma
anemia
immune checkpoint inhibitors
title Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin
title_full Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin
title_fullStr Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin
title_full_unstemmed Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin
title_short Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin
title_sort asymptomatic jejunal metastatic melanoma a case report of anemia of uncertain origin
topic jejunal metastasis
melanoma
anemia
immune checkpoint inhibitors
url https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1324&context=jmms
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AT andreeaparosanu asymptomaticjejunalmetastaticmelanomaacasereportofanemiaofuncertainorigin
AT cristinaorlovslavu asymptomaticjejunalmetastaticmelanomaacasereportofanemiaofuncertainorigin
AT catalinpiriianu asymptomaticjejunalmetastaticmelanomaacasereportofanemiaofuncertainorigin
AT raduvrabie asymptomaticjejunalmetastaticmelanomaacasereportofanemiaofuncertainorigin
AT iulianslavu asymptomaticjejunalmetastaticmelanomaacasereportofanemiaofuncertainorigin
AT valentincalu asymptomaticjejunalmetastaticmelanomaacasereportofanemiaofuncertainorigin