Iptacopan Reduces Proteinuria and Stabilizes Kidney Function in C3 Glomerulopathy

Iptacopan Reduces Proteinuria and Stabilizes Kidney Function in C3 Glomerulopathy

Introduction: C3 glomerulopathy (C3G) is a complex, chronic, ultra rare, progressive primary glomerulonephritis, resulting from alternative complement pathway overactivation, leading to kidney failure in most patients, and frequent recurrence in transplants. Iptacopan (LNP023) is an oral, proximal c...

Full description

Saved in:
Bibliographic Details
Main Authors: Carla M. Nester, Ute Eisenberger, Alexandre Karras, Moglie le Quintrec, Liz Lightstone, Manuel Praga, Giuseppe Remuzzi, Maria José Soler, Junhao Liu, Matthias Meier, Ronda Tawfik, Guido Junge, Andrea Biondani, Angelo J. Trapani, Nicholas J.A. Webb, Edwin K.S. Wong
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Kidney International Reports
Subjects:
C3 glomerulopathy
C3G
complement pathway
iptacopan
kidney
transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924019892
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2468024924019892

Similar Items