Postoperative intravenous parecoxib sodium followed by oral celecoxib post total knee arthroplasty in osteoarthritis patients (PIPFORCE): a multicentre, double-blind, randomised, placebo-controlled trial

Postoperative intravenous parecoxib sodium followed by oral celecoxib post total knee arthroplasty in osteoarthritis patients (PIPFORCE): a multicentre, double-blind, randomised, placebo-controlled trial

Objectives To evaluate the morphine-sparing effects of the sequential treatment versus placebo in subjects undergoing total knee arthroplasty (TKA), the effects on pain relief, inflammation control and functional rehabilitation after TKA and safety.Design Double-blind, pragmatic, randomised, placebo...

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Main Authors: Jianhao Lin, Liyuan Tao, Xisheng Weng, Bin Feng, Ye Li, Jin Jin, Yu Fan, Qianyu Zhuang, Jin Lin, Wenwei Qian, Yanyan Bian, Yulong Li, Yulei Dong, Huiming Peng, Na Gao, Tiezheng Sun, Miaofeng Zhang, Shigui Yan, Bin Shen, Fuxing Pei
Format: Article
Language:English
Published: BMJ Publishing Group 2020-01-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/1/e030501.full
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https://bmjopen.bmj.com/content/10/1/e030501.full

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