Nano-based perivascular intervention sustains a nine-month long-term suppression of intimal hyperplasia in vein grafts

Nano-based perivascular intervention sustains a nine-month long-term suppression of intimal hyperplasia in vein grafts

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Open vascular reconstructions (OVR), including bypass grafts and dialysis access, are standard treatments for cardiovascular and renal diseases. Unfortunately, OVR often fail largely due to intimal hyperplasia (IH), and there are no clinical methods to prevent this complication. Perivascular drug ad...

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Bibliographic Details
Main Authors: Takuro Shirasu, Go Urabe, Nisakorn Yodsanit, Yitao Huang, Ruosen Xie, Matthew S. Stratton, Matthew Joseph, Zhanpeng Zhang, Yuyuan Wang, Jing Li, Runze Tang, Lynn M. Marcho, Li Yin, Eric W. Kent, Kaijie Zhang, Ki Ho Park, Bowen Wang, K. Craig Kent, Shaoqin Gong, Lian-Wang Guo
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-02-01
Series:Bioactive Materials
Subjects:
Post-surgery failure of open vascular reconstructions
Intimal hyperplasia
Vein graft
Arteriovenous fistula
Perivascular drug delivery
Pericelle
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24004493
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