Curcumin/piperine modulates the butyrate levels and alleviates diabetic kidney disease via Nrf2/HO-1 signaling pathway

Objectives This study investigates whether curcumin/piperine (C/P) modulates butyrate levels and mitigates diabetic kidney disease (DKD) via the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway.Methods Eight-week-old mice were treated with C/P for 12 weeks...

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Bibliographic Details
Main Authors: Yinan Zhu, Lina Sun, Zhaoan Guo, Peiqing Xin, Feng Huang, Lei Song, Yulin Man, Miaomiao Ren, Zhongwei Ma, Ying Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
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Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2538117
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