Genotype Distribution and High-Risk Factors Analysis of Group B Streptococcus in Late-Stage Pregnant Women in the Linyi Region

Conclusion: The colonization rate of GBS in the reproductive tract of pregnant women in late pregnancy in the Linyi region is 7.07%. Having a college degree or above, absence of pregnancy vomiting, elevated levels of albumin, globulin, direct bilirubin, glutamyl transferase, and total bile acids, an...

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Bibliographic Details
Main Authors: Weiping Zhou, Xiaoyan Chen, Jie Chen, Xiuhua Zheng, Xueqiang Zhang, Yubin Chen, Yuehua Pan, Chunling Ma
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/ijm/9910073
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Summary:Conclusion: The colonization rate of GBS in the reproductive tract of pregnant women in late pregnancy in the Linyi region is 7.07%. Having a college degree or above, absence of pregnancy vomiting, elevated levels of albumin, globulin, direct bilirubin, glutamyl transferase, and total bile acids, and decreased levels of alkaline phosphatase and lactate dehydrogenase are high-risk factors for GBS infection; ST10, ST19, ST529, and ST862 are the main genotypes prevalent in this region; there are regional differences in the distribution of GBS genotypes and CC groups; there are statistically significant differences in the distribution of virulence factors among GBS strains with different MLST genotypes (p<0.05); GBS shows high sensitivity to penicillin drugs and can still be used as the preferred medication for the prevention and treatment of GBS infection.
ISSN:1687-9198