Pyridazine Based Compounds with PARP-1 Inhibitory Activity

Pyridazine-containing compounds have been identified as potent PARP1 inhibitors. The PARP is a family of enzymes essential for many cellular processes such as DNA repair, genomic stability, and apoptosis, also known as poly(ADP-ribose) synthetases and poly(ADP-ribose) transferases.PARP1 (Poly (ADP-r...

Full description

Saved in:
Bibliographic Details
Main Authors: Norhan A. Abdelrahman, Mai Y. Jaballah, Ahmed A. Al-Karmalawy, Khaled A. M. Abouzid
Format: Article
Language:English
Published: Ain Shams University 2023-12-01
Series:Archives of Pharmaceutical Sciences Ain Shams University
Subjects:
Online Access:https://aps.journals.ekb.eg/article_320648.html
Tags: Add Tag
No Tags, Be the first to tag this record!