TraceEyeDisease: a web-based database for investigating trace elements and their imbalances in eye diseases
Abstract Eye diseases remain a significant global health concern, with trace elements crucial in maintaining ocular health and preventing ocular disorders. In ocular health, trace elements have been recognized as critical factors influencing the development and progression of multiple eye diseases....
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| Format: | Article |
| Language: | English |
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BMC
2024-11-01
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| Series: | BMC Research Notes |
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| Online Access: | https://doi.org/10.1186/s13104-024-06981-8 |
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| author | Jyoti Kant Choudhari Hritik Yadav Usha Chouhan |
| author_facet | Jyoti Kant Choudhari Hritik Yadav Usha Chouhan |
| author_sort | Jyoti Kant Choudhari |
| collection | DOAJ |
| description | Abstract Eye diseases remain a significant global health concern, with trace elements crucial in maintaining ocular health and preventing ocular disorders. In ocular health, trace elements have been recognized as critical factors influencing the development and progression of multiple eye diseases. In this study, we conducted a thorough literature search through PubMed to acquire data concerning different eye diseases associated with trace elements. These diseases are essential in trace element imbalances or deficiencies in their progression. Our approach included a meticulous compilation of information from various databases, systematically integrated into a carefully curated database. In total, we identified 178 distinct genes that encode proteins linked to fourteen trace elements in this comprehensive list. A web-based database designed to formulate evidence-based hypotheses regarding the impact of trace element deficiency and imbalance on eye diseases was presented using Shiny R. This study underscores the vital role of trace elements in preserving ocular health. The Shiny R application facilitates subsequent investigations, fostering enhanced insights into public health, clinical practices, and eye disease research. The URL of TraceEyeDiseas is https://tredis.shinyapps.io/TraceEyeDisease/ . |
| format | Article |
| id | doaj-art-a9cf2d6b5ef04e0b8a20af28e4ce3eb8 |
| institution | Kabale University |
| issn | 1756-0500 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj-art-a9cf2d6b5ef04e0b8a20af28e4ce3eb82024-11-17T12:08:17ZengBMCBMC Research Notes1756-05002024-11-011711710.1186/s13104-024-06981-8TraceEyeDisease: a web-based database for investigating trace elements and their imbalances in eye diseasesJyoti Kant Choudhari0Hritik Yadav1Usha Chouhan2Maulana Azad National Institute of TechnologyGovt. V.Y.T. Post Graduate Autonomous CollegeMaulana Azad National Institute of TechnologyAbstract Eye diseases remain a significant global health concern, with trace elements crucial in maintaining ocular health and preventing ocular disorders. In ocular health, trace elements have been recognized as critical factors influencing the development and progression of multiple eye diseases. In this study, we conducted a thorough literature search through PubMed to acquire data concerning different eye diseases associated with trace elements. These diseases are essential in trace element imbalances or deficiencies in their progression. Our approach included a meticulous compilation of information from various databases, systematically integrated into a carefully curated database. In total, we identified 178 distinct genes that encode proteins linked to fourteen trace elements in this comprehensive list. A web-based database designed to formulate evidence-based hypotheses regarding the impact of trace element deficiency and imbalance on eye diseases was presented using Shiny R. This study underscores the vital role of trace elements in preserving ocular health. The Shiny R application facilitates subsequent investigations, fostering enhanced insights into public health, clinical practices, and eye disease research. The URL of TraceEyeDiseas is https://tredis.shinyapps.io/TraceEyeDisease/ .https://doi.org/10.1186/s13104-024-06981-8Eye diseasesDatabaseTrace elementsShiny R |
| spellingShingle | Jyoti Kant Choudhari Hritik Yadav Usha Chouhan TraceEyeDisease: a web-based database for investigating trace elements and their imbalances in eye diseases BMC Research Notes Eye diseases Database Trace elements Shiny R |
| title | TraceEyeDisease: a web-based database for investigating trace elements and their imbalances in eye diseases |
| title_full | TraceEyeDisease: a web-based database for investigating trace elements and their imbalances in eye diseases |
| title_fullStr | TraceEyeDisease: a web-based database for investigating trace elements and their imbalances in eye diseases |
| title_full_unstemmed | TraceEyeDisease: a web-based database for investigating trace elements and their imbalances in eye diseases |
| title_short | TraceEyeDisease: a web-based database for investigating trace elements and their imbalances in eye diseases |
| title_sort | traceeyedisease a web based database for investigating trace elements and their imbalances in eye diseases |
| topic | Eye diseases Database Trace elements Shiny R |
| url | https://doi.org/10.1186/s13104-024-06981-8 |
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