Rapid effects of valproic acid on the fetal brain transcriptome: implications for brain development and autism

Abstract There is an increased incidence of autism among the children of women who take the anti-epileptic, mood-stabilizing drug, valproic acid (VPA) during pregnancy; moreover, exposure to VPA in utero causes autistic-like symptoms in rodents and non-human primates. Analysis of RNA-seq data obtain...

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Bibliographic Details
Main Authors: Susan G. Dorsey, Evelina Mocci, Malcolm V. Lane, Bruce K. Krueger
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-03179-1
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