Oestrogen Receptor Alpha in Myocyte Maintains Muscle Regeneration in Duchenne Muscular Dystrophy

Oestrogen Receptor Alpha in Myocyte Maintains Muscle Regeneration in Duchenne Muscular Dystrophy

ABSTRACT Background Oestrogen receptor alpha (ERα) plays an important role in maintaining mitochondrial function and regulating metabolism in skeletal muscle. However, its alterations and potential mechanisms in Duchenne muscular dystrophy (DMD) remain incompletely understood. In this study, we demo...

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Main Authors: Xiaofei Huang, Sijia Li, Huna Wang, Lei Zhao, Xihua Li, Shusheng Fan, Wanting Hu, Haowei Tong, Guangyao Guo, Dengqiu Xu, Luyong Zhang, Zhenzhou Jiang, Qinwei Yu
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Duchenne muscular dystrophy
fulvestrant
oestradiol
oestrogen receptor alpha
skeletal muscle regeneration
Online Access:https://doi.org/10.1002/jcsm.13807
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https://doi.org/10.1002/jcsm.13807

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