Impact of Species and Tissue Differences on In Vitro Glucuronidation of Diclofenac

Impact of Species and Tissue Differences on In Vitro Glucuronidation of Diclofenac

Background: The aim of this study is to determine the impact of species and tissue differences on the glucuronidation of diclofenac in vitro. Method: Microsomes from different species (rat, monkey, mouse, dog, and human) and rat and human tissues (liver, intestine, and kidney) were used to assess th...

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Bibliographic Details
Main Authors:	Eric Asare, Shalom Emmanuel, Ting Du, Huan Xie, Dong Liang, Song Gao
Format:	Article
Language:	English
Published:	MDPI AG 2024-12-01
Series:	Molecules
Subjects:	diclofenac glucuronidation species differences tissue differences UGT
Online Access:	https://www.mdpi.com/1420-3049/29/24/5867
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