Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Study 2021
Abstract. Background:. Epidemiological studies have demonstrated a causal relationship between ambient ozone (O3) and mortality from chronic obstructive pulmonary disease (COPD), which is the only outcome considered in the Global Burden of Disease Study 2021 for O3. This study aims to evaluate the...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2024-12-01
|
| Series: | Chinese Medical Journal |
| Online Access: | http://journals.lww.com/10.1097/CM9.0000000000003415 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841550789688950784 |
|---|---|
| author | Yixuan Jiang Fanshu Yan Haidong Kan Maigeng Zhou Peng Yin Renjie Chen Jing Ni |
| author_facet | Yixuan Jiang Fanshu Yan Haidong Kan Maigeng Zhou Peng Yin Renjie Chen Jing Ni |
| author_sort | Yixuan Jiang |
| collection | DOAJ |
| description | Abstract.
Background:. Epidemiological studies have demonstrated a causal relationship between ambient ozone (O3) and mortality from chronic obstructive pulmonary disease (COPD), which is the only outcome considered in the Global Burden of Disease Study 2021 for O3. This study aims to evaluate the temporal trend and spatial distribution of the COPD burden attributable to O3 across China from 1990 to 2021.
Methods:. The ambient O3 concentrations in China were estimated. Based on the methodology framework and standard analytical methods applied in the Global Burden of Disease Study 2021, we estimated the annual number, age-standardized rate, and percentage of deaths and disability-adjusted life-years (DALYs) from COPD attributable to O3 pollution during 1990–2021 at the national and provincial levels in China.
Results:. In 2021, a total of 125.7 (95% uncertainty interval [UI], 26.4–228.3) thousand deaths and 1917.5 (95% UI, 398.7–3504.6) thousand DALYs from COPD were attributable to ambient O3 pollution in China, accounting for 9.8% (95% UI, 2.1–17.0%) and 8.1% (95% UI, 1.8–14.1%) of the total COPD deaths and DALYs, respectively. Generally, a higher burden was observed among males, the elderly, and the population residing in regions with worse health conditions. The age-standardized rates of COPD deaths and DALYs per 100,000 populations ranged from 0.5 (95% UI, 0–1.4) and 8.1 (95% UI, 0.7–20.9) in Hong Kong to 22.8 (95% UI, 3.9–43.5) and 396.6 (95% UI, 68.9–763.7) in Xizang. From 1990 to 2021, there was a notable decrease in the age-standardized rates of COPD-related deaths (68.2%, 95% UI, 60.1–74.9%) and DALYs (71.5%, 95% UI, 63.7–77.6%), especially in regions with poor health conditions. However, the attributable numbers and percentages changed relatively marginally.
Conclusions:. Ambient O3 pollution is a major contributor to the COPD burden in China. Our findings highlight the significant spatial heterogeneity across different provinces and underscore the implementation of geographically tailored policies to effectively reduce O3 pollution and alleviate the associated disease burden. |
| format | Article |
| id | doaj-art-a8f349e95b774f8aa3ad0c420408198c |
| institution | Kabale University |
| issn | 0366-6999 2542-5641 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Chinese Medical Journal |
| spelling | doaj-art-a8f349e95b774f8aa3ad0c420408198c2025-01-10T01:10:24ZengWolters KluwerChinese Medical Journal0366-69992542-56412024-12-01137243126313510.1097/CM9.0000000000003415202412200-00015Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Study 2021Yixuan Jiang0Fanshu Yan1Haidong Kan2Maigeng Zhou3Peng Yin4Renjie Chen5Jing Ni1 School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai 200032, China2 National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China1 School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai 200032, China2 National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China2 National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China1 School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai 200032, ChinaAbstract. Background:. Epidemiological studies have demonstrated a causal relationship between ambient ozone (O3) and mortality from chronic obstructive pulmonary disease (COPD), which is the only outcome considered in the Global Burden of Disease Study 2021 for O3. This study aims to evaluate the temporal trend and spatial distribution of the COPD burden attributable to O3 across China from 1990 to 2021. Methods:. The ambient O3 concentrations in China were estimated. Based on the methodology framework and standard analytical methods applied in the Global Burden of Disease Study 2021, we estimated the annual number, age-standardized rate, and percentage of deaths and disability-adjusted life-years (DALYs) from COPD attributable to O3 pollution during 1990–2021 at the national and provincial levels in China. Results:. In 2021, a total of 125.7 (95% uncertainty interval [UI], 26.4–228.3) thousand deaths and 1917.5 (95% UI, 398.7–3504.6) thousand DALYs from COPD were attributable to ambient O3 pollution in China, accounting for 9.8% (95% UI, 2.1–17.0%) and 8.1% (95% UI, 1.8–14.1%) of the total COPD deaths and DALYs, respectively. Generally, a higher burden was observed among males, the elderly, and the population residing in regions with worse health conditions. The age-standardized rates of COPD deaths and DALYs per 100,000 populations ranged from 0.5 (95% UI, 0–1.4) and 8.1 (95% UI, 0.7–20.9) in Hong Kong to 22.8 (95% UI, 3.9–43.5) and 396.6 (95% UI, 68.9–763.7) in Xizang. From 1990 to 2021, there was a notable decrease in the age-standardized rates of COPD-related deaths (68.2%, 95% UI, 60.1–74.9%) and DALYs (71.5%, 95% UI, 63.7–77.6%), especially in regions with poor health conditions. However, the attributable numbers and percentages changed relatively marginally. Conclusions:. Ambient O3 pollution is a major contributor to the COPD burden in China. Our findings highlight the significant spatial heterogeneity across different provinces and underscore the implementation of geographically tailored policies to effectively reduce O3 pollution and alleviate the associated disease burden.http://journals.lww.com/10.1097/CM9.0000000000003415 |
| spellingShingle | Yixuan Jiang Fanshu Yan Haidong Kan Maigeng Zhou Peng Yin Renjie Chen Jing Ni Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Study 2021 Chinese Medical Journal |
| title | Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Study 2021 |
| title_full | Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Study 2021 |
| title_fullStr | Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Study 2021 |
| title_full_unstemmed | Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Study 2021 |
| title_short | Burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across China and its provinces, 1990–2021: An analysis for the Global Burden of Disease Study 2021 |
| title_sort | burden of chronic obstructive pulmonary disease attributable to ambient ozone pollution across china and its provinces 1990 2021 an analysis for the global burden of disease study 2021 |
| url | http://journals.lww.com/10.1097/CM9.0000000000003415 |
| work_keys_str_mv | AT yixuanjiang burdenofchronicobstructivepulmonarydiseaseattributabletoambientozonepollutionacrosschinaanditsprovinces19902021ananalysisfortheglobalburdenofdiseasestudy2021 AT fanshuyan burdenofchronicobstructivepulmonarydiseaseattributabletoambientozonepollutionacrosschinaanditsprovinces19902021ananalysisfortheglobalburdenofdiseasestudy2021 AT haidongkan burdenofchronicobstructivepulmonarydiseaseattributabletoambientozonepollutionacrosschinaanditsprovinces19902021ananalysisfortheglobalburdenofdiseasestudy2021 AT maigengzhou burdenofchronicobstructivepulmonarydiseaseattributabletoambientozonepollutionacrosschinaanditsprovinces19902021ananalysisfortheglobalburdenofdiseasestudy2021 AT pengyin burdenofchronicobstructivepulmonarydiseaseattributabletoambientozonepollutionacrosschinaanditsprovinces19902021ananalysisfortheglobalburdenofdiseasestudy2021 AT renjiechen burdenofchronicobstructivepulmonarydiseaseattributabletoambientozonepollutionacrosschinaanditsprovinces19902021ananalysisfortheglobalburdenofdiseasestudy2021 AT jingni burdenofchronicobstructivepulmonarydiseaseattributabletoambientozonepollutionacrosschinaanditsprovinces19902021ananalysisfortheglobalburdenofdiseasestudy2021 |