Protein Phosphatase 2A Promotes CD8+ T Cell Effector Function through the Augmentation of CD28 Costimulation

Protein phosphatase 2A (PP2A) is one of the most abundant serine/threonine phosphatases and plays critical roles in regulating cell fate and function. We previously showed that PP2A regulates the differentiation of CD4+ T cells and the development of thymocytes. Nevertheless, its role in CD8+ T cell...

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Bibliographic Details
Main Authors: Kaixiang Zhu, Deepak Rohila, Yuanling Zhao, Dmytro Shytikov, Lize Wu, Fan Zhao, Shurong Hu, Qin Xu, Xuexiao Jin, Linrong Lu
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2025-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0545
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