Cell‐free DNA from ascites identifies clinically relevant variants and tumour evolution in patients with advanced ovarian cancer

Cell‐free DNA from ascites identifies clinically relevant variants and tumour evolution in patients with advanced ovarian cancer

The emergence of targeted therapies has transformed ovarian cancer treatment. However, biomarker profiling for precision medicine is limited by access to quality, tumour‐enriched tissue samples. The use of cell‐free DNA (cfDNA) in ascites presents a potential solution to this challenge. In this stud...

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Bibliographic Details
Main Authors: Bonnita Werner, Elyse Powell, Jennifer Duggan, Marilisa Cortesi, Yeh Chen Lee, Vivek Arora, Ramanand Athavale, Michael Dean, Kristina Warton, Caroline E. Ford
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Molecular Oncology
Subjects:
ascites
biomarkers
cell‐free DNA
homologous recombination deficiency
ovarian cancer
precision medicine
Online Access:https://doi.org/10.1002/1878-0261.13710
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https://doi.org/10.1002/1878-0261.13710

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