Evaluating the usefulness of C5 and C5AR1 as genetic biomarkers of IgA-mediated vasculitis

Evaluating the usefulness of C5 and C5AR1 as genetic biomarkers of IgA-mediated vasculitis

Abstract Background IgA-mediated vasculitis (IgAV) is a complex inflammatory disease. Unravelling its genetic background would allow us to identify genetic biomarkers that may be used as additional tools in its daily management, helping to solve the clinical challenge that this vasculitis entails. C...

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Main Authors: Joao Carlos Batista-Liz, Vanesa Calvo-Río, María Sebastián Mora-Gil, María Teresa Leonardo, Ana Cristina Peñalba, Luis Martín-Penagos, Javier Narváez, Belén Sevilla-Pérez, José Luis Callejas-Rubio, Ligia Gabrie, Rafael Gálvez Sánchez, Luis Caminal-Montero, Paz Collado, María José Rodríguez Valls, Diego de Argila, Patricia Quiroga-Colina, Esther Francisca Vicente-Rabaneda, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Ricardo Blanco, Verónica Pulito-Cueto, Raquel López-Mejías
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Molecular Medicine
Subjects:
Biomarkers
C5
C5AR1
Genetics
IgA Vasculitis
Online Access:https://doi.org/10.1186/s10020-025-01313-3
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https://doi.org/10.1186/s10020-025-01313-3

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