Colitis Cystica Profunda Mimicking Malignancy

Colitis cystica profunda (CCP) is nonneoplastic lesion characterised by the presence of intramural mucosal herniation or mucus-containing cysts in the colon and rectum. <200 cases have been reported in the English literature searched to the best of our knowledge. The cause of the lesion is not cl...

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Bibliographic Details
Main Authors: Sheenam Azad, Brijesh Thakur, Seema Acharya, Shefali Kamboj, Rajiv Kumar Azad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Indian Journal of Medical Specialities
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Online Access:https://journals.lww.com/10.4103/injms.injms_98_23
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Summary:Colitis cystica profunda (CCP) is nonneoplastic lesion characterised by the presence of intramural mucosal herniation or mucus-containing cysts in the colon and rectum. <200 cases have been reported in the English literature searched to the best of our knowledge. The cause of the lesion is not clear and a confident diagnosis can be made only on histopathology. We present a series of three cases with clinical and/or radiological possibility of colonic neoplastic etiology. These cases include two females of 32 and 76 years of age, respectively, and a 51-year-old male patient presented with nonspecific symptoms (loss of weight/appetite, episode of blood-mixed stools, pain in abdomen, constipation, and burning micturition). Rescected colonic segments were sent for histological examination, and the final histopathological diagnosis of all three cases was CCP. CCP is a rare benign condition that may mimic carcinoma clinically and grossly at times. The surgeon and pathologist must be aware of this entity to avoid radical treatment.
ISSN:0976-2884
0976-2892