Beta-Cell-Derived Extracellular Vesicles: Mediators of Intercellular Communication in the Islet Microenvironment in Type 1 Diabetes

Beta-Cell-Derived Extracellular Vesicles: Mediators of Intercellular Communication in the Islet Microenvironment in Type 1 Diabetes

Type 1 diabetes (T1D) is a chronic autoimmune disorder characterised by an autoimmune response specifically mounted against the insulin-producing beta cells. Within the islet, high cellular connectivity and extensive vascularisation facilitate intra-islet communication and direct crosstalk with the...

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Bibliographic Details
Main Authors: Mette C. Dekkers, Xudong Pu, Agustin Enciso-Martinez, Arnaud Zaldumbide
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
type 1 diabetes
ER stress
extracellular vesicles
inflammation
Online Access:https://www.mdpi.com/2073-4409/13/23/1996
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