Pentraxin-3 modulates hepatocyte ferroptosis and the innate immune response in LPS-induced liver injury

Pentraxin-3 modulates hepatocyte ferroptosis and the innate immune response in LPS-induced liver injury

Abstract The liver plays a crucial role in the immune response during endotoxemia and is one of the critical targets for sepsis-related injuries. As a secretory factor involved in inflammation, pentraxin-3 (PTX3) has been demonstrated to regulate hepatic homeostasis; however, the relationship betwee...

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Main Authors: Huitong Wang, Zhaojie Su, Yunyun Qian, Baojie Shi, Hao Li, Wenbin An, Yi Xiao, Cheng Qiu, Zhixiang Guo, Jianfa Zhong, Xia Wu, Jiajia Chen, Ying Wang, Wei Zeng, Linghui Zhan, Jie Wang
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Molecular Biomedicine
Subjects:
PTX3
LPS
Liver
Crosstalk
Macrophage polarization
Online Access:https://doi.org/10.1186/s43556-024-00227-6
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https://doi.org/10.1186/s43556-024-00227-6

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