Phenotypically distinguishable eosinophilic cells do not impact epithelial functions in a triple-culture in vitro intestinal model

Phenotypically distinguishable eosinophilic cells do not impact epithelial functions in a triple-culture in vitro intestinal model

The small intestine is a complex assembly of different cell types, such as enterocytes, secretory, immune, stromal and nervous cells. Due to this complexity, studying human tissue function ex vivo is challenging. As surrogate systems, in vitro co-culture models have been proven to be reliable and af...

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Main Authors: Christoph Benkstein, Laurin Mosig, Daniel Vondran, Heidi Schlichting, Lea Kissing, Bente Wohlert, Ida Gensmer, Larissa Nogueira de Almeida, Peter König, Kerstin Fibelkorn, Anna Kordowski, Stefanie Derer-Petersen, Christian Sina, Yves Laumonnier
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
eosinophils
electron microscopy
triple culture system
Caco-2
HT29-MTX cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1641651/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1641651/full

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