Integrin β8 Facilitates Macrophage Infiltration and Polarization by Regulating CCL5 to Promote LUAD Progression

Abstract The tumor microenvironment (TME) influences cancer progression and metastasis. Integrin β8 (ITGβ8), a member of the integrin family, is upregulated in various cancers. In this study, it is determined as a key factor that mediates the interaction between lung adenocarcinoma (LUAD) cells and...

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Bibliographic Details
Main Authors: Lei Song, Xi Yu, Yang Wu, Wenwen Zhang, Yu Zhang, Yanchi Shao, Zhenxin Hou, Chen Yang, Yue Gao, Yanbin Zhao
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
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Online Access:https://doi.org/10.1002/advs.202406865
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