Comparison of combined intranasal dexmedetomidine and ketamine versus chloral hydrate for pediatric procedural sedation: a randomized controlled trial

Comparison of combined intranasal dexmedetomidine and ketamine versus chloral hydrate for pediatric procedural sedation: a randomized controlled trial

Background We hypothesized that intranasal combination of dexmedetomidine (2 μg/kg) and ketamine (3 mg/kg) (IN DEXKET) improves the success rate of sedation in pediatric patients compared with chloral hydrate (CH; 50 mg/kg). Methods This prospective, two-center, single-blinded, randomized controlled...

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Bibliographic Details
Main Authors: Young-Eun Jang, Eun-Young Joo, Jung-Bin Park, Sang-Hwan Ji, Eun-Hee Kim, Ji-Hyun Lee, Hee-Soo Kim, Jin-Tae Kim
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2025-06-01
Series:Korean Journal of Anesthesiology
Subjects:
administration, intranasal
chloral hydrate
conscious sedation
deep sedation
dexmedetomidine
drug-related side effects and adverse reactions
hypnotics and sedatives
ketamine
pediatrics
Online Access:http://ekja.org/upload/pdf/kja-24815.pdf
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